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| Description: Naive T lymphocytes home to lymph nodes as a result of L-selectin binding to its ligan on High Endothelial Venules (HEVs), which are present only in lymph nodes, and as a result of binding chemokines (CCL19 and CCL21) displayed on the surface of the HEV. Activated T lymphocytes, including effector cells, home to sites of infection in peripheral tissues, and this migration is mediated by E- and P-selectins and integrins, and chemokines that are produced at sites of infection. Additional chemokines and chemokine receptors, besides the ones shown, are involved in effector/memory T cell migration. Picture Stats: Views: 5638 Filesize: 54.15kB Height: 480 Width: 746 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=1504 |