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| Description: The HBV life cycle involves a sequence of events allowing for viral entry into hepatocytes and import of HBV DNA into the hepatocyte nucleus, followed by viral replication, assembly, and excretion of mature virions into the extracellular space (96). Molecular targets of antiviral therapy based on the HBV life cycle are noted, including classes of investigational antiviral agents and corresponding sites of activity. Abbreviations: cccDNA, covalently closed circular double-stranded DNA; HAP, heteroaryldihydropy rimidines; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; pgRNA, pre-genomic RNA; siRNA, short interfering RNA. Picture Stats: Views: 3139 Filesize: 77.03kB Height: 461 Width: 624 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=19554 Keywords: virus hepatitis |