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PET Scans of a Patient with Parkinsonian Symptoms

PET Scans of a Patient with Parkinsonian Symptoms
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Description: The scans show uptake of radioactive L-DOPA in the basal ganglia of a patient with parkinsonian symptoms induced by a toxic chemical before and after receiving a transplant of fetal dopaminergic neurons. (a) Preoperative scan. (b) Scan taken 13 months postoperatively. The increased uptake of L-DOPA indicates that the fetal transplant was secreting dopamine. (Adapted from Widner, H., Tetrud, J., Rehncrona, S., et al. New England Journal of Medicine, 1992, 327, 1556–1563. Scans reprinted with permission.)
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