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| Description: Functional MRI scans show increased activity in the dorsolateral prefrontal cortex and the periaqueductal gray matter of the midbrain of subjects who showed decrease sensitivity to pain in response to administration of a placebo. (From Wager, T. D., Rilling, J. K., Smith, E. E., Sokolik, A., Casey, K. L., Davidson, R. J., Kosslyn, S. M., Rose, R. M., and Cohen, J. D. Science, 2004, 303, 1162–1166. Copyright © American Association for the Advancement of Science. Reprinted with permission.)
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