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| Description: The acetylcholinergic REM-ON cell is located in the dorsal pons. The figure shows (a) action potentials during 60-minute intervals during waking, slow-wave sleep, and REM sleep, and (b) rate of firing just before and after the transition from slow-wave sleep to REM sleep. The increase in activity begins approximately 80 seconds before the onset of REM sleep. (Adapted from El Mansari, M., Sakai, K., and Jouvet, M. Experimental Brain Research, 1989, 76, 519–529.)
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