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| Description: (a) Environmental cues present in the room provide information that permits the animals to orient themselves in space. (b) According to the task, start positions are variable or fixed. Normally, rats are released from a different position on each trial. If they are released from the same position every time, the rats can learn to find the hidden platform through stimulus-response learning. (c) The graphs show the performance of normal rats and rats with hippocampal lesions using variable or fixed start positions. Hippocampal lesions impair acquisition of the relational task. (d) Representative samples show the paths followed by normal rats and rats with hippocampal lesions on the relational task (variable start positions). (Adapted from Eichenbaum, H. Nature Reviews: Neuroscience, 2000, 1, 41–50. Data from Eichenbaum et al., 1990.)
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