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Conformations of single-stranded nucleic acids

Conformations of single-stranded nucleic acids
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Description: Secondary and Tertiary Structure of Nucleic Acids

a) The random coil structure of denatured single strands. There is flexibility of rotation of residues and no specific structure.

b) Stacked-basostructure adapted by non–self-complementary single strands under “native” conditions. Bases stack to pull the chain into a helix, but there is no H-bonding.

c) Hairpin structures formed by self-complementary sequences; the chain folds back on itself to make a stem–loop structure.

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