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| Description: a) A silent, or synonymous, mutation has occurred in the codon for residue 2 (CAC to CAT). b) A missense, or nonsynonymous, mutation has occurred in the codon for residue 6 (GAG to GTG). This is the sickle-cell mutation. c) A nonsense mutation has introduced a stop signal after the codon for residue 7 (AAG to TAG), terminating the chain prematurely. d) A frameshift mutation has occurred by deletion of a single T residue. The rest of the chain, with a completely altered sequence, will continue to be produced until a stop signal is encountered in the new frame. Both (c) and (d) would result in b-thalassemia. Picture Stats: Views: 228 Filesize: 194.76kB Height: 406 Width: 1138 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34133 |