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Co-translational insertion and folding of transmembrane helices in an integral membrane protein

Co-translational insertion and folding of transmembrane helices in an integral membrane protein
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Description: Some parts of the protein (in this case, the loops) are conducted across the bilayer through the translocon; transmembrane portions exit the translocon and remain embedded in the bilayer.

The transmembrane helices fold after they are inserted.

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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34330
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