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The induced conformational change in hexokinase

The induced conformational change in hexokinase
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Description: The binding of glucose to hexokinase induces a significant conformational change in the enzyme.

The enzyme is a single polypeptide chain, with two major domains.

Notice how the obvious cleft between the domains (panel a) closes around the glucose molecule
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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34370
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