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A model for mixed inhibition

A model for mixed inhibition
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Description: The inhibitor binds at a site on the enzyme surface different from that of the substrate.

In this simplified example, the inhibitor binds to both free enzyme and the ES complex.

EI has reduced substrate binding affinity compared to free enzyme.

The EIS complex cannot carry out the catalytic event.

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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34396
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