Picture Gallery

Search For: 

Irreversible inhibition by adduct formation

Irreversible inhibition by adduct formation
Previous Image | Next Image
Description: Diisopropyl fluorophosphate (DFP) reacts with a serine group on a protein to form a covalent adduct.

The covalent bond renders the catalytically important serine ineffective in catalysis.

The adduct also may block substrate binding to the active site.

Picture Stats:
Views: 226
Filesize: 40.55kB
Height: 611 Width: 449
Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34399
Return to Gallery