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| Description: By inactivating individual enzymes, mutations and enzyme inhibitors help identify the metabolic roles of enzymes. The steps of a hypothetical metabolic pathway are identified by analysis of mutants defective in individual steps of the pathway. We can identify metabolite C as the substrate for enzyme III by the absence of this enzyme in mutants that accumulate C. We know that D and E follow C in the pathway because feeding either D or E to mutants defective in enzyme III bypasses the genetic block and allows the cells to grow. Picture Stats: Views: 266 Filesize: 121.13kB Height: 607 Width: 468 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34471 |