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| Description: Phosphofructokinase catalyzes a second ATP-dependent phosphorylation, to give a hexose derivative, fructose-1,6-bisphosphate (FBP), phosphorylated at both carbons 1 and 6. Transferring the carbonyl oxygen from carbon 1 to carbon 2 has two important effects: The hydroxyl group generated at carbon 1 can be readily phosphorylated in the reaction 3. It also sets up the sugar for a symmetric aldol cleavage in reaction 4. The phosphofructokinase reaction is the primary step at which glycolysis is regulated. Picture Stats: Views: 281 Filesize: 48.34kB Height: 197 Width: 963 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34511 |