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Bypass 1: Conversion of Pyruvate to Phosphoenolpyruvate

Bypass 1: Conversion of Pyruvate to Phosphoenolpyruvate
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Description: The bypass of pyruvate kinase begins in the mitochondrion and involves two reactions.

Pyruvate carboxylase catalyzes the ATP- and biotin-dependent conversion of pyruvate to oxaloacetate.

The enzyme requires acetyl-CoA as an allosteric activator
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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34526
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