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Model of the purinosome

Model of the purinosome
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Description:
The figure shows a hypothetical model for a multi-enzyme complex in animal cells that transforms PRPP to IMP.

Serine hydroxymethyltransf erase (SHMT) and the trifunctional enzyme C1-tetrahydrofolate (THF) synthase, also proposed to be part of the complex, channel one-carbon units from serine into 10-formyl-THF for the transformylase reactions.

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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34828
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