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Structure of the homodimeric thymidylate synthase from E. coli

Structure of the homodimeric thymidylate synthase from E. coli
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Description: Structure of the homodimer with bound folate cofactor (yellow) and FdUMP (red).

Active site region of the orange subunit in (a) showing the ternary complex formed between 5,10-methylene-THF, FdUMP, and Cys146.

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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34857
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