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| Description: 1. Rapid synapse, leading to opening of gated ion channels. 2. Interaction of 5-hydroxytryptamine (5HT, or serotonin) with adenylate cyclase, causing activation of cAMP-activated protein kinase. 3. Effect of longer-term stimulation, with protein kinases (e.g., MAPK) translocating to the nucleus and stimulating specific gene transcription by phosphorylating certain transcription factors such as CREB. 4. Stimulation of localized protein synthesis by still undefined interactions with translation complexes. Picture Stats: Views: 219 Filesize: 81.72kB Height: 472 Width: 352 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34895 |