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A complete kinetic scheme for a single nucleotide addition

A complete kinetic scheme for a single nucleotide addition
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Description: Pre-steady-state kinetic analysis of DNA polymerase reactions shows that dNTP binding to a polymerase-DNA complex precedes a major conformational change that must occur before “chemistry,” that is, the formation and breakage of chemical bonds.

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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34974
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