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Simplified view of retrovirus life cycle

Simplified view of retrovirus life cycle
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Description: The RNA genome contains long terminal repeats, to one of which a tRNA molecule binds.

Primer extension, partial RNA digestion, and circularization generate a substrate for extensive DNA synthesis.

Ultimately, a circular duplex DNA molecule is formed, and it is the likely substrate for integration into a host chromosome.

Evidence suggests that two viral RNA molecules must interact at step 2 or 3.

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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34980
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