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| Description: Depending upon the route of introduction of oG to DNA, the pathways shown can cause either GC ---> AT or AT ---> GC transversions. MutT hydrolyzes 8-oxo-dGTP and prevents its incorporation during DNA replication. MutM excises oG from a C-G base pair to begin BER. MutY excises A from an A-oG base pair in another BER process, allowing an additional possibility for correcting an error in the next round of replication. Picture Stats: Views: 292 Filesize: 19.02kB Height: 236 Width: 267 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=34996 |