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Backtracking in an elongation complex

Backtracking in an elongation complex
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Description: Above, the 3’ terminus of the transcript is in the active site (denoted by Mg2+).

Below, the enzyme has slipped backward, leaving the transcript terminus at the end of a nonbase-paired RNA tail, some five nucleotides long.

Transcription can resume either by forward sliding of polymerase back to the structure depicted above or, more likely, by cleavage of the non-base-paired part of the transcript, creating a new base-paired 3’ terminus.

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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=35038
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