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Kinetic analysis of spliceosome assembly

Kinetic analysis of spliceosome assembly
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Description: Each step in the assembly pathway was shown to be reversible, with rate constants in the forward direction as shown.

Reversibility has not yet been detected in the activation step shown nor in mRNA release.

SF3b is a protein splicing factor and NTC is a multiprotein complex called Prp19.

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Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=35060
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