Previous Image | Next Image |
Description: A protein with a nuclear localization signal (NLS) binds to importin. The complex binds to a nuclear pore and passes through. Within the nucleus Ran-GTP binds to the importin-cargo complex and displaces the cargo. The resultant Ran-importin complex is returned to the cytoplasm, where Ran-bound GTP is hydrolyzed to GDP. Ran-GDP returns to the nucleus, and its bound GDP is exchanged for GTP (not shown). Picture Stats: Views: 356 Filesize: 94.93kB Height: 378 Width: 314 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=35108 |