Picture Gallery

Search For: 

A schematic view of delivery of a protein, synthesized in cytoplasm, into the nucleus

A schematic view of delivery of a protein, synthesized in cytoplasm, into the nucleus
Previous Image | Next Image
Description: A protein with a nuclear localization signal (NLS) binds to importin.
The complex binds to a nuclear pore and passes through.
Within the nucleus Ran-GTP binds to the importin-cargo complex and displaces the cargo.
The resultant Ran-importin complex is returned to the cytoplasm, where Ran-bound GTP is hydrolyzed to GDP.
Ran-GDP returns to the nucleus, and its bound GDP is exchanged for GTP (not shown).

Picture Stats:
Views: 356
Filesize: 94.93kB
Height: 378 Width: 314
Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=35108
Return to Gallery