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| Description: Gene fusion in the 9;22 translocation. Part of the BCR gene on chromosome 22 is moved to chromosome 9 and fuses with part of the C-ABL gene on that chromosome to form a hybrid gene. Expression of the hybrid gene produces a hybrid BCR-ABL protein that continuously signals for cell division in white blood cells. Overproduction of these cells results in CML. Picture Stats: Views: 194 Filesize: 135.92kB Height: 1467 Width: 1500 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=44637 |