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| Description: Scanning electron micrographs of (a) normal red blood cells and (b) sickled red blood cells. As shown above the micrographs, a missense mutation in the ?-globin gene (which codes for a subunit of hemoglobin) changes the sixth amino acid in the ?-globin polypeptide from a glutamic acid to a valine. (c) This micrograph shows how this alteration to the structure of ?-globin causes the formation of abnormal fibrelike structures. In normal cells, hemoglobin proteins do not form fibres.
Picture Stats: Views: 4865 Filesize: 60.57kB Height: 353 Width: 850 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=462 Keywords: A missense mutation that causes red blood cells to sickle in sickle-cell anemia. |