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| Description: (a) Transcription is repressed in high-phosphate conditions. (b) In low-phosphate conditions, Pho4 joins Pho2 at UASp1, and NuA4 directs acetylation of nearby nucleosomes. The SWI/SNF complex attaches, leading to the ejection of nucleosomes −1 to −4. RNA polymerase II and general transcription factors initiate PHO5 transcription(a) Transcription is repressed in high-phosphate conditions. (b) In low-phosphate conditions, Pho4 joins Pho2 at UASp1, and NuA4 directs acetylation of nearby nucleosomes. The SWI/SNF complex attaches, leading to the ejection of nucleosomes −1 to −4. RNA polymerase II and general transcription factors initiate PHO5 transcription (a) High phosphate results in transcription repression é PHOS UASp1 UASp2 TATA Nucleosome —5 —4 —3 —2 —1 +1 number (b) Low phosphate results in transcription activation UASp1 UASp2 TATA -5 —4 -3 —2 —1 +1 Nucleosome ejection, SWVSNF binding, and transcription activation SWI/SNF /. _ . UASp1 UASp -5 TATA +1 Picture Stats: Views: 60 Filesize: 590.87kB Height: 2342 Width: 1984 Source: https://biology-forums.com/index.php?action=gallery;sa=view;id=49316 |