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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
On average, the stomach produces 2 L of hydrochloric acid per day.
In 1835 it was discovered that a disease of silkworms known as muscardine could be transferred from one silkworm to another, and was caused by a fungus.