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On average, the stomach produces 2 L of hydrochloric acid per day.
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Earwax has antimicrobial properties that reduce the viability of bacteria and fungus in the human ear.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.
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It is difficult to obtain enough calcium without consuming milk or other dairy foods.