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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
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Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.