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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.
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Human stomach acid is strong enough to dissolve small pieces of metal such as razor blades or staples.
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Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.