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In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.
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The FDA recognizes 118 routes of administration.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
![Alternative forms of surgeries involving the uterus, ovaries, and fallopian tubes. The solid lines i](https://biology-forums.com/gallery/47/medium_14755_26_10_12_5_30_30_9697737.jpeg)
![First-pass effect: (a) drugs are absorbed; (b) drugs enter hepatic portal circulation and go directl](https://biology-forums.com/gallery/47/medium_46687_12_12_14_7_07_21_195641052.jpeg)