Author Question: Give three examples of autoimmune diseases, including their clinical manifestations and ... (Read 71 times)

theo · **on:** Jun 25, 2018

Give three examples of autoimmune diseases, including their clinical manifestations and pathogenesis.

What will be an ideal response?

Question 2

Explain increased enzyme synthesis in chronic alcoholism.

What will be an ideal response?

shaikhs · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

See table on page 87 for complete list
Glomerulonephritis: antibodies form against basement membrane; some cases from deposition of antigen-antibody complexes in the glomerular basement membrane resulting in inflammation of renal glomeruli
SLE: formation of antinuclear antibodies causing widespread organ damage to the joints, kidneys, heart muscle, blood vessels resulting in systemic disease such as joint pain, skin rash
Hashimoto's thyroiditis: antibodies to thyroid gland cause injury and inflammation of the thyroid, resulting in hypothyroidism

Answer to Question 2

Increased elimination, metabolism, or detoxification of drugs or chemicals by increased synthesis of enzymes in the SER occurs in alcoholism; a person is much more able to metabolize alcohol as the body's response to chronic exposure to alcohol.