Give three examples of autoimmune diseases, including their ...

[theo]

Give three examples of autoimmune diseases, including their clinical manifestations and pathogenesis.
 
  What will be an ideal response?

Question 2

Explain increased enzyme synthesis in chronic alcoholism.
 
  What will be an ideal response?

[shaikhs]

Answer to Question 1

See table on page 87 for complete list
Glomerulonephritis: antibodies form against basement membrane; some cases from deposition of antigen-antibody complexes in the glomerular basement membrane resulting in inflammation of renal glomeruli
SLE: formation of antinuclear antibodies causing widespread organ damage to the joints, kidneys, heart muscle, blood vessels resulting in systemic disease such as joint pain, skin rash
Hashimoto's thyroiditis: antibodies to thyroid gland cause injury and inflammation of the thyroid, resulting in hypothyroidism

Answer to Question 2

Increased elimination, metabolism, or detoxification of drugs or chemicals by increased synthesis of enzymes in the SER occurs in alcoholism; a person is much more able to metabolize alcohol as the body's response to chronic exposure to alcohol.

[theo]

TYSM

[debra928]

Excellent