Which of the following disorders is manifested primarily in ...

[tingc95]

Which of the following disorders is manifested primarily in males?
 
  a. Cystic fibrosis
  b. Neurofibromatosis
  c. Muscular dystrophy
  d. Klinefelter syndrome

Question 2

When the nurse is teaching the staff about X-linked recessive disorders, which information should the nurse include? (select all that apply)
 
  a. The trait is seen much more often in fe-males than in males.
  b. The trait is never transmitted from father to son.
  c. The gene can be transmitted through a se-ries of carrier females.
  d. The gene is passed from an affected father to all his daughters.
  e. The trait never skips generations.

[ntsoane kedibone]

Answer to Question 1

ANS: C
Muscular dystrophy is manifested primarily in males. Cystic fibrosis, neurofibromatosis, and Klinefelter syndrome are manifested in both males and females.

Answer to Question 2

ANS: B, C, D
The principles of X-linked recessive inheritance include: the trait is seen much more often in males than in females; the trait is never transmitted from father to son; the gene can be transmit-ted through a series of carrier females; the gene is passed from an affected father to all his daughters, who, as phenotypically normal carriers, transmit it to approximately half their sons, who are affected. X-linked recessive disorders can skip generations since it is a one in four chance.

[tingc95]

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