A 26-year-old man who survived childhood acute lymphocytic ...

[melly21297]

A 26-year-old man who survived childhood acute lymphocytic leukemia (ALL), one of the most common childhood cancers, now complains of weakness, fatigue, and shortness of breath.
 
  His treatment for ALL likely included anthracyclines. What is the most likely cause of his symptoms?
  A)
  Recurrence of ALL
  B)
  CNS problems resulting from childhood chemotherapy
  C)
  Heart failure resulting from childhood chemotherapy
  D)
  Hormonal dysfunction resulting from childhood chemotherapy

Question 2

Which of the following enzymes listed below is responsible for cancer cells' ability to prevent aging of the cells and contributes to cellular immortality that is so characteristic of this disease process?
 
  A)
  Oxidoreductase
  B)
  Telomerase
  C)
  Hydrolase
  D)
  Isomerase

[sylvia]

Answer to Question 1

Ans:
C

Feedback:

The patient's symptoms resemble those of congestive heart failure. The anthracyclines, such as doxorubicin and daunorubicin, are associated with the risk for developing cardiomyopathy and heart failure.

Answer to Question 2

Ans:
B

Feedback:

Some cells have telomerase, an enzyme that rebuilds telomeres and lessens or prevents shortening. Cancer cells have high levels of telomerase, which prevents senescence and contributes to the cellular immortality that characterizes cancer.