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Though methadone is often used to treat dependency on other opioids, the drug itself can be abused. Crushing or snorting methadone can achieve the opiate "rush" desired by addicts. Improper use such as these can lead to a dangerous dependency on methadone. This drug now accounts for nearly one-third of opioid-related deaths.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.
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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.