Clearance (CL) of a drug is defined as which of the following?
A. The rate of elimination by all routes normalized to the concentration of drug, in some biological fluids
B. A measure of the apparent space the body has available to contain the drug
C. The time required for an amount of drug in blood to decline to one-half its measured value
D. The fraction of drug dose reaching the systemic circulation following administration by any route
Question 2
Phenobarbital is classified as a:
A. Cardiac glycoside.
B. Anti arrhythmic.
C. Analgesic, antipyretic, and anti-inflammatory.
D. Sedative and hypnotic.
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