This topic contains a solution. Click here to go to the answer

Author Question: A 28-year-old woman sees her family physician complaining of easy bruising and menorrhagia. She has ... (Read 78 times)

dmcintosh

  • Hero Member
  • *****
  • Posts: 517
A 28-year-old woman sees her family physician complaining of easy bruising and menorrhagia. She has a platelet count of 60 x 109/L.
 
  All other hematology and routine coagulation tests are normal. She has a platelet-associated immunoglobulin G (IgG) autoantibody in her serum. Which of the following is most likely?
 
  a. Chronic immune thrombocytopenic purpura
  b. Thrombotic thrombocytopenic purpura
  c. Acute immune thrombocytopenic purpura
  d. Hemolytic uremic syndrome

Question 2

What kind of antibody causes neonatal alloimmune thrombocytopenia?
 
  a. Maternal antibody against a fetal platelet antigen inherited from the father
  b. Fetal antibody directed against maternal platelet antigen
  c. Fetal antibody against a fetal platelet antigen inherited from the father
  d. Maternal autoantibody against a mother's platelet antigen



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

stillxalice

  • Sr. Member
  • ****
  • Posts: 339
Answer to Question 1

ANS: A
Chronic immune thrombocytopenic purpura is most often seen in women between the ages of 20 and 50 years of age. Patients most often complain of easy bruising, recurrent epistaxis, and menorrhagia. Platelet destruction in chronic immune thrombocytopenic purpura is the result of an IgG autoantibody, with various membrane glycoproteins being the most frequent targets.

Answer to Question 2

ANS: A
Neonatal alloimmune thrombocytopenia develops when a mother, during pregnancy, develops an alloantibody against a platelet antigen inherited by the fetus from the father. These antibodies cross the placenta, bind to the antigen-bearing fetal platelets, and cause their premature destruction.




dmcintosh

  • Member
  • Posts: 517
Reply 2 on: Jun 25, 2018
Great answer, keep it coming :)


tuate

  • Member
  • Posts: 332
Reply 3 on: Yesterday
Wow, this really help

 

Did you know?

Immunoglobulin injections may give short-term protection against, or reduce severity of certain diseases. They help people who have an inherited problem making their own antibodies, or those who are having certain types of cancer treatments.

Did you know?

In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.

Did you know?

According to the CDC, approximately 31.7% of the U.S. population has high low-density lipoprotein (LDL) or "bad cholesterol" levels.

Did you know?

Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.

Did you know?

Approximately one in three babies in the United States is now delivered by cesarean section. The number of cesarean sections in the United States has risen 46% since 1996.

For a complete list of videos, visit our video library