A patient who is not on heparin and has no history of a factor ...

[mmm]

A patient who is not on heparin and has no history of a factor deficiency has a prolonged partial thromboplastin time (PTT). Select the test that should be performed next.
 
  a. High-sensitivity C-reactive protein
  b. Mixing studies for lupus anticoagulant
  c. Thrombin time (TT)
  d. Lipid panel

Question 2

A thrombosis risk testing profile is ordered on a patient being treated with warfarin for a blood clot in the leg. Select the best course of action.
 
  a. Run the tests immediately.
  b. Reject the order.
  c. Perform only the tests for protein C and protein S.
  d. Recommend the testing be postponed until the warfarin is discontinued.

[yuyiding]

Answer to Question 1

ANS: B
The lupus anticoagulant results in a prolonged PTT. It is characterized by lack of correction when the patient plasma is mixed 1:1 with normal platelet poor plasma and the PTT repeated. None of the other listed findings prolong the PTT.

Answer to Question 2

ANS: D
Testing should be postponed until the warfarin has been discontinued for 10 to 14 days. Warfarin blocks the normal synthesis of vitamin Kdependent proteins, which include protein C and protein S.

[mmm]

TYSM

[sultansheikh]

Thanks for the timely response, appreciate it