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Author Question: What is the purest form of factor VIII that is available for treating a bleeding patient with ... (Read 55 times)

yoooooman

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on: Jun 25, 2018
What is the purest form of factor VIII that is available for treating a bleeding patient with hemophilia A?
 
  a. Cryoprecipitate
  b. Recombinant factor VIII concentrate
  c. Fresh frozen plasma
  d. Factor VIII concentrate prepared by chemical concentration

Question 2

What test is useful for detection of a female carrier of hemophilia A?
 
  a. PTT
  b. PT
  c. Factor VIII to VWF ratio
  d. VWF antigen test


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cegalasso

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: B
Recombinant deoxyribonucleic acid (DNA) technology provides a high-purity factor VIII concentrate.

Answer to Question 2

ANS: C
Approximately 90 of female carriers of hemophilia A are detected using the ratio of factor VIII activity to VWF antigen. This is because WVF production is unaffected by factor VIII deficiency, so it should be normal in a female hemophilia A carrier, whereas the factor VIII activity will be less than that of VWF. Thus a discrepancy exists in the concentration of these two proteins.


yoooooman

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

nathang24

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Reply 3 on: Yesterday
Excellent

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