What substance is known to inactivate cyclooxygenase, causing ...

[newbem]

What substance is known to inactivate cyclooxygenase, causing impairment of platelet function?
 
  a. Aspirin
  b. Calcium
  c. Tylenol
  d. Vitamin K

Question 2

Two children in the same family have recurrent, chronic bruising in multiple sites, repeated long-lasting epistaxis, and minor bleeding after dental work. Which type of disorder is most likely?
 
  a. Localized, acquired, anatomic
  b. Localized, congenital, anatomic
  c. Generalized, congenital, systemic
  d. Generalized, acquired, systemic

[mistyjohnson]

Answer to Question 1

ANS: A
Aspirin inactivates the enzyme cyclooxygenase, blocking thromboxane A2 production and causing impairment of platelet function (called aspirin effect). Thromboxane A2 causes Ca+2 to be released and promotes platelet aggregation and vasoconstriction.

Answer to Question 2

ANS: C
Because the two affected children are in the same family, this is most likely congenital. Recurrent, chronic bruising in multiple sites, along with long-lasting epistaxis and minor bleeding after dental work, make this generalized and systemic rather than localized and anatomic.

[newbem]

Thank you

[mistyjohnson]

No problemo