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Author Question: Which of the following are mature pan-B cell markers? a. CD4 and CD8 b. CD33 and CD45 c. CD19 ... (Read 77 times)

ishan

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on: Jun 25, 2018
Which of the following are mature pan-B cell markers?
 
  a. CD4 and CD8
  b. CD33 and CD45
  c. CD19 and CD20
  d. CD33 and CD59

Question 2

Malignant proliferation of plasma cells with osteolytic bone lesions and the presence of monoclonal immunoglobulin in the serum describe:
 
  a. Waldenstrm macroglobulinemia
  b. Marginal zone B-cell lymphoma
  c. Follicle center lymphoma
  d. Plasma cell myeloma


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Leostella20

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: C
CD19 and CD20 mark all mature B cells.

Answer to Question 2

ANS: D
Plasma cell myeloma is characterized by a monoclonal proliferation of malignant plasma cells. A monoclonal spike is usually observed after serum protein electrophoresis. Patients often have osteolytic bone lesions.


ishan

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Reply 2 on: Jun 25, 2018
Thanks for the timely response, appreciate it

peter

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Reply 3 on: Yesterday
Excellent

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