Author Question: A patient in the hospital for a hemolytic crisis after an infection has Heinz bodies when his blood ... (Read 59 times)

kfurse

  • Hero Member
  • *****
  • Posts: 590
A patient in the hospital for a hemolytic crisis after an infection has Heinz bodies when his blood is incubated with crystal violet. The fluorescent enzyme-screening test for G6PD is normal. Select the best course of action.
 
  a. Repeat the red cell examination with new methylene blue stain.
  b. Repeat the enzyme test several weeks after the hemolytic crisis.
  c. Perform an osmotic fragility test.
  d. Perform a haptoglobin test.

Question 2

What is the best test to confirm the diagnosis of PK?
 
  a. PK enzyme assay
  b. Reticulocyte count
  c. Haptoglobin test
  d. Urine hemosiderin test



parshano

  • Sr. Member
  • ****
  • Posts: 333
Answer to Question 1

ANS: B
Reticulocytes have higher levels of G6PD than older red cells. Because reticulocytes are increased after a hemolytic episode, their presence can give a false-negative (normal) result in the screening test for G6PD. Testing should be repeated when the patient has returned to normal, with a normal cohort of red cells (all ages).

Answer to Question 2

ANS: A
The clinician makes a diagnosis of PK deficiency by performing an assay for the enzyme.



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question


 

Did you know?

Recent studies have shown that the number of medication errors increases in relation to the number of orders that are verified per pharmacist, per work shift.

Did you know?

Elderly adults are living longer, and causes of death are shifting. At the same time, autopsy rates are at or near their lowest in history.

Did you know?

Vaccines cause herd immunity. If the majority of people in a community have been vaccinated against a disease, an unvaccinated person is less likely to get the disease since others are less likely to become sick from it and spread the disease.

Did you know?

The training of an anesthesiologist typically requires four years of college, 4 years of medical school, 1 year of internship, and 3 years of residency.

Did you know?

Most women experience menopause in their 50s. However, in 1994, an Italian woman gave birth to a baby boy when she was 61 years old.

For a complete list of videos, visit our video library