What is responsible for erythrocyte deformability and maintaining ...

[tiara099]

What is responsible for erythrocyte deformability and maintaining cell shape?
 
  a. Membrane proteins
  b. Na+ and K+ pump
  c. Membrane lipids
  d. Ca2+ pump

Question 2

What important function does 2,3-BPG perform?
 
  a. Maintains iron in the hemoglobin molecule in the ferrous state
  b. Prevents oxidative injury to the red cell
  c. Facilitates the delivery of oxygen to tissue
  d. Aids in the exchange of membrane lipids with lipids in plasma

[amit]

Answer to Question 1

ANS: A
Proteins in the membrane are responsible for maintaining the shape and deformability of the red cell. Cation pumps maintain the Na+ and K+ gradient within the red cell. Membrane lipids form the fluid foundation into which the membrane proteins are inserted. The Ca2+ pump maintains intracellular levels of Ca2+.

Answer to Question 2

ANS: C
2,3-BPG plays a critical role in the effective transport of oxygen to tissue. It is produced via a shunt off the EMP. Elevations in 2,3-BPG are seen in a number of situations such as anemia; they result in more effective delivery of oxygen to tissue. It has no role in the other functions listed.