A sickle solubility test is requested STAT on a 45-year-old patient who is to have surgery very soon. The technologist receives the sample and immediately takes out the reagent from the refrigerator and performs the test. It comes back positive.
The surgery is postponed until hemoglobin electrophoresis is performed, and it shows a normal distribution of adult hemoglobins. What is the most likely reason for the discrepant result?
a. There was a false positive on the sickle solubility test because of the cold reagent.
b. The hemoglobin electrophoresis findings need to be confirmed on acid gel.
c. There was a false negative on the sickle solubility test because of inadequate mixing.
d. The wrong patient was drawn.
Question 2
Given an RBC count of 3.25 1012/L, a hemoglobin of 9.0 g/dL, and a hematocrit of 25, how will the red cells appear under PB smear examination?
a. Normocytic
b. Macrocytic
c. Microcytic
d. Hyperchromic
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