A 44-year-old female presents for her routine examination. She complains of tiredness and difficulty in breathing when she exerts herself. Her DAT is positive with polyspecific AHG and anti-IgG. Her hemoglobin is 7.5 gm/dl,
and her indices suggest a normocytic, normochromic anemia. Her peripheral blood smear shows the presence of spherocytes. What is the most likely diagnosis?
a. CAD
b. Drug-induced IHA
c. WAIHA
d. Mixed-type AIHA
Question 2
Paroxysmal cold hemoglobinuria is confirmed by a positive:
a. Antibody class IgM.
b. Thermal amplitude of antibody over 20 C.
c. Donath-Landsteiner test
d. Cold agglutinin test.
