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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
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More than one-third of adult Americans are obese. Diseases that kill the largest number of people annually, such as heart disease, cancer, diabetes, stroke, and hypertension, can be attributed to diet.
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The people with the highest levels of LDL are Mexican American males and non-Hispanic black females.