Answer to Question 1
ANS: A
Acanthosis nigricans is associated with insulin resistance. It is most prevalent in individuals who are obese and in Blacks and Hispanics. Onset is usually in youth. It is an area of darkly pigmented skin often within the skin folds.
Answer to Question 2
ANS: A
With vitiligo, the patient often describes a history of the progressive development of small, multiple areas of depigmentation that, over time, become larger and confluent. There is no overlying scale or vesicle development. Any area of skin can be involved. The hair in the affected area may also lose pigmentation. There is a higher incidence of vitiligo in patients with autoimmune disorders, particularly those affecting the endocrine system, including hypothyroidism, diabetes mellitus, and Addison's disease.