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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
Vaccines prevent between 2.5 and 4 million deaths every year.
Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Serum cholesterol testing in adults is recommended every 1 to 5 years. People with diabetes and a family history of high cholesterol should be tested even more frequently.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.