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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
More than 50% of American adults have oral herpes, which is commonly known as "cold sores" or "fever blisters." The herpes virus can be active on the skin surface without showing any signs or causing any symptoms.
Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
Approximately 500,000 babies are born each year in the United States to teenage mothers.
Malaria was not eliminated in the United States until 1951. The term eliminated means that no new cases arise in a country for 3 years.

